(237) Hybridization of Hydrangea arborescens and H. involucrata

Hydrangea

Tragia Cannabina & Involucrata

Sir,?I noticed in the " British Medical Journal" of the 28th September last, page 719, a communication from Mr. Oldacres, M.B.C.S., that by handling the plant named Primula obconica an obstinate rash is produced, attended with dyspeptic symptoms. 1 beg to bring to your notice that there are two plants in this part of the country, very common in shady places, known as the Tragia eannaMna and Tra...

237 Editorial

The paper in the present issue of the APJCP by Mandal and his colleagues offers a disturbing contrast to generally positive conclusions of the recent special article by Breen et al (2001) on progress in cancer screening in the USA. The underlying differences in basic assumptions are of essential significance if we are to advocate national screening programs in Asia. A simple comparison points t...

Lipoma arborescens of the knee.

Lipoma arborescens is a rare intra-articular lesion, characterised by diffuse replacement of the subsynovial tissue by mature fat cells, producing prominent villous transformation of the synovium. The aetiology of this benign condition is unknown. We describe six cases involving the knee, discussing the symptoms, diagnosis and treatment.

Dmd047662 230..237

Carfilzomib, an irreversible proteasome inhibitor, has a favorable safety profile and significant antitumor activity in patients with relapsed and refractory multiple myeloma (MM). Here we summarize the clinical pharmacokinetics (PK), metabolism, and drug-drug interaction (DDI) profile of carfilzomib. The PK of carfilzomib, infused over 2–10 minutes, was evaluated in patients with solid tumors ...